Home > Profiles > Hsueh-Chia Chang

Hsueh-Chia Chang

Hsueh-Chia Chang

Contact Info

Email: hchang@nd.edu
Phone: 574-631-5697
Office: 118B Cushing Hall
Website: http://www.nd.edu/~changlab/
Curriculum Vitae

Summary of Activities/Interests

Assistant Professor, University of California, Santa Barbara (1980-1983)
Associate Professor, University of California, Santa Barbara (1983-84)
Associate Professor, University of Houston (1984-1987)
Professor, University of Notre Dame (1987-1998)
Chair, Chemical Engineering, University of Notre Dame (1989-1995)
Senior Visitor, DAMTP, Cambridge University (1993)
Bayer Professor, University of Notre Dame (1998-Present)
Director, Center for Microfluidics and Medical Diagnostics (2003-Present)

Prof Chia Chang, the Bayer Professor of Engineering and Director of the Center for Microfluidics and Medical Diagnostics, is a leading researcher in micro/nanofluidics, particularly in the area of nano-electrokinetics. He has just published a Cambridge Univ Press book on the subject. His group combines analysis and physical insight to discover new physical phenomena and to develop patented devices for technology transfer. More than 20 of his former PhD students are now teaching in leading academic universities throughout the world. Prof Chang is the founding Editor of Biomicrofluidics, an American Institute of Physics journal. He has received many awards including the Frankiel Award from the American Physical Society and the Presidential Young Investigator Award from NSF. A fellow of APS, he has delivered more than 20 keynote/plenary lectures and has more than 200 publications with over 3000 citations.

Education

B.S. Caltech (1976)

M.S. Princeton (1977)

Ph.D. Princeton (1980)

Biography

We explore and apply electrokinetic phenomena to develop new diagnostic and micro/nanofluidic devices that are portable, sensitive and fast. We are particularly interested in designing new molecular sensing and analysis technologies based on AC and non-equilibrium electrokinetics at the surface of nanoporous membranes and nanostructure assemblies. Devices and techniques under development include DNA/RNA sensing, on-chip pH actuation, Carbon Nanotube/Nanocolloid molecular sensors, nanofuidic diodes, plasmonic sensors etc. Three technologies have been licensed to FCubed LLC of Notre Dame Innovation Park and we are integrating them into diagnostic devices for environmental, medical and food safety applications.

Publications

I.-F. Cheng, X. Cheng, S. Basuray, and H.-C. Chang. "A Rapid Field-Use Assay for Mismatch Number and Location of Hybridized DNA's". Lab-on-a-Chip, 10:828-831, 2010.

S. Basuray, S. Ajian, A. Mahon, A.R. and H.-C. Chang. "Shear and AC Field Enhanced Carbon Nanotube Impedance Assay for Rapid, Sensitive and Mismatch-Discriminating DNA Hybridization". ACS Nano, 3:1823, 2009.

Awards

Francois N. Frenkiel Award
Given on November 24, 1991 by American Physical Society

Regent's Junior Faculty Award
Given on June 15, 1980 by University of California, Santa Barbara

Fellow of the Americal Physical Society
Given on September 29, 1997 by American Physical Society

Sigma Xi Outstanding Research Award
Given on April 27, 1990 by University of Notre Dame

Presidential Young Investigator
Given on May 31, 1985 by National Science Foundation