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Ryan Roeder

Ryan K. Roeder


Phone: 574-631-7003

Office: 148 Multidisciplinary Building


B.S., Materials Engineering - Purdue University, 1994

Ph.D. Materials Engineering - Purdue University, 1999


Dr. Roeder's research interests broadly span biomaterials, including nanoparticles for targeted contrast agents and drug delivery, and scaffolds for regenerating tissues, as well biomechanics, including the mechanobiology and micromechanics of musculoskeletal tissues.  Dr. Roeder's research has been supported by the National Science Foundation (NSF), the National Institutes of Health (NIH), the U.S. Army Medical Research and Materiel Command (USAMRMC), the Congressionally-Directed Medical Research Programs (CDMRP), as well as private foundations and corporations.  Dr. Roeder’s research group is multidisciplinary, including students with backgrounds in biomedical engineering, materials engineering, mechanical engineering, chemical engineering, and chemistry.  Ph.D. graduates have been placed in postdoctoral positions, research hospitals, biomedical industry positions, and faculty positions.

Selected Recent Publications

L.E. Cole, T. Vargo-Gogola and R.K. Roeder, “Contrast-enhanced X-ray detection of microcalcifications in radiographically dense mammary tissue using targeted gold nanoparticles,” ACS Nano, in press.

A.P. Baumann, M.W. Aref, T.L. Turnbull, A.G. Robling, G.L. Niebur, M.R. Allen and R.K. Roeder, “Development of an In Vivo Rabbit Ulnar Loading Model,” Bone, 75, 55-61 (2015). 10.1016/j.bone.2015.01.022

R.J. Kane, H.E. Weiss-Bilka, M.J. Meagher, Y. Liu, J.A. Gargac, G.L. Niebur, D.R. Wagner and R.K. Roeder, “Hydroxyapatite reinforced collagen scaffolds with improved architecture and mechanical properties,” Acta Biomaterialia, 17, 16-25 (2015). doi:10.1016/j.actbio.2015.01.031

L.E. Cole, R.D. Ross, J.M.R. Tilley, T. Vargo-Gogola and R.K. Roeder, “Gold nanoparticles as contrast agents in X-ray imaging and computed tomography,” Nanomedicine, 10 [2] 321-341 (2015). doi:10.2217/nnm.14.171

L.E. Cole, T. Vargo-Gogola and R.K. Roeder, “Contrast-enhanced X-ray detection of breast microcalcifications in a murine model using targeted gold nanoparticles,” ACS Nano, 8 [7], 7486-7496 (2014). doi:10.1021/nn5027802

T.L. Turnbull, A.P. Baumann and R.K. Roeder, “Fatigue microcracks that initiate fracture are located near elevated intracortical porosity but not elevated mineralization,” J. Biomechanics, 47 [12] 3135-3142 (2014). doi:10.1016/j.jbiomech.2014.06.022

R.D. Ross, L.E. Cole, J.M.R. Tilley and R.K. Roeder, “Effect of Functionalized Gold Nanoparticle Size on X-Ray Attenuation and Binding Affinity to Hydroxyapatite,” Chem. Mater., 26 [2], 1187-1194 (2014). doi:10.1021/cm4035616

L.E. Cole, T. Vargo-Gogola and R.K. Roeder, “Bisphosphonate-functionalized gold nanoparticles for contrast-enhanced X-ray detection of breast microcalcifications,” Biomaterials, 35 [7] 2312-2321 (2014). doi:10.1016/j.biomaterials.2013.11.077

M.J. Meagher, B. Leone, T.L. Turnbull, R.D. Ross, Z. Zhang and R.K. Roeder, “Dextran-encapsulated barium sulfate nanoparticles prepared for aqueous dispersion as an X-ray contrast agent,” J. Nanopart. Res., 15 [12] 2146 (10 pages) (2013). doi:10.1007/s11051-013-2146-8

R.K. Roeder, “Mechanical Characterization of Biomaterials”; in Characterization of Biomaterials.  Edited by A. Bandyopadhyay and S. Bose.  Elsevier, Inc., Amsterdam, 2013.  doi:10.1016/B978-0-12-415800-9.00003-6

T.L. Conrad, D.J. Jaekel, S.M. Kurtz and R.K. Roeder, “Effects of the mold temperature on the mechanical properties and crystallinity of hydroxyapatite whisker reinforced polyetheretherketone scaffolds,” J. Biomed. Mater. Res., 101B [4] 576-583 (2013). doi:10.1002/jbm.b.32859

R.K. Roeder and T.L. Conrad, “Bioactive Polyaryletherketone Composites”; pp. 163-179 in the PEEK Biomaterials Handbook. Edited by S.M. Kurtz.  Elsevier, Inc., Amsterdam, 2012. doi:10.1016/B978-1-4377-4463-7.10011-9

Summary of Activities/Interests

Biomaterials, Nanoparticles, Scaffolds, Composites, Bone Mechanics