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Joshua Shrout

Joshua D Shrout

Email: joshua.shrout@nd.edu

Phone: 574-631-1726

Office: 214A Cushing Hall (Mailing address: 156 Fitzpatrick Hall)

Education

Ph.D, University of Iowa, 2002

M.S., Civil and Environmental Engineering, Marquette University, 1998

B.S., Environmental Engineering, Northwestern University, 1994

Biography

Education/Training:

Post-doc. University of Washington/ University of Iowa—Microbiology (2003-2007)

Post-doc. University of Iowa—Civil and Environmental Engineering (2002-2003)

Current Appointments:

Professor Shrout has been a faculty member in the Department Civil and Environmental Engineering and Earth Sciences since 2007 and a concurrent faculty member in the Department of Biological Sciences since 2010.

Center Affiliations:

Advanced Diagnostics and Therapeutics

Eck Institute for Global Health

Summary of Activities/Interests

 

The Shrout Research Group investigates "sociomicrobiology" and community actions of bacteria that are important to medicine and the environment. Much of our work researches the development of bacterial biofilms.

 

Biofilms are surface-associated communities of bacteria. Surprisingly, very few factors that regulate biofilm growth on various surfaces such as human tissue, medical implants, water intake pipes, teeth, soil particles, or even other microorganisms are understood even for "simple" bacteria. We use an interdisciplinary research approach to understand how physical and chemical environmental cues influence biological behavior of biofilms.

Relatedly, our group researches the motility of bacteria on surfaces. Many bacteria, such as the organism Pseudomonas aeruginosa, are capable of controlling their surface motility as an initial step in biofilm development. We are working to understand how bacteria orchestrate their response(s).



 

News

24th Midwest Microbial Pathogenesis Conference at Notre Dame Highlighted by "Journal of Bacteriology"

May 10, 2018

The University of Notre Dame hosted the 24th Midwest Microbial Pathogenesis Conference in August 2017. Topics of the conference were highlighted in the June 2018 issue of "Journal of Bacteriology."

Study reveals how bacteria communicate in groups to avoid antibiotics

April 27, 2018

In a new study published in the Journal of Biological Chemistry (JBC), researchers from the University of Notre Dame and the University of Illinois at Urbana-Champaign have found that the bacterium Pseudomonas aeruginosa, a pathogen that causes pneumonia, sepsis and other infections, communicates distress signals within a group of bacteria in response to certain antibiotics.

Study Reveals how Bacteria Communicate in Groups to Avoid Antibiotics

April 26, 2018

In a new study published in the Journal of Biological Chemistry (JBC), researchers from the University of Notre Dame and the University of Illinois at Urbana-Champaign have found that the bacterium Pseudomonas aeruginosa, a pathogen that causes pneumonia, sepsis and other infections, communicates distress signals within a group of bacteria in response to certain antibiotics. This communication was found to vary across the colony and suggests that this bacterium may develop protective behaviors that contribute to its ability to tolerate some antibiotics.

Blue-sky Biomedical Projects Launched by New Funding

August 30, 2016

Advanced Diagnostics & Therapeutics (AD&T), a strategic research initiative at the University of Notre Dame, has announced the recipients of its Discovery Fund awards for 2016. Innovative research includes efforts to treat Parkinson’s disease, understand heart disease and strokes, tackle bacterial drug resistance.

New Notre Dame Paper Offers Novel Insights into Pathogen Behavior

December 18, 2014

A new study by a team of researchers that includes University of Notre Dame scientists Joshua Shrout and Mark Alber provides new insights into the behavior of an important bacterial pathogen.