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Matthew Webber

Matthew J Webber

Email: mwebber@nd.edu

Phone: 574-631-4246

Office: 205B McCourtney Hall

Education

Ph.D. Biomedical Engineering, Northwestern University, 2011

M.S Biomedical Engineering, Northwestern University 2009

B.S. Chemical Engineering, University of Notre Dame, 2006

Summary of Activities/Interests

Research interests:

• Supramolecular Biomaterials: The use of non-covalent molecular recognition motifs to engineer highly tunable, dynamic, modular, and bioactive materials for biomedical and biological applications (see Webber et al. Nature Materials 2016)

• “Smart” Drug Delivery and Diagnostics: The development of new strategies to deliver drugs, therapeutic proteins, or diagnostic agents that are capable of sensing and responding to spatiotemporal indicators of disease and/or overcoming physiologic barriers imposed by complexities of disease pathology (see Webber & Langer Chem Soc Rev 2017)

• Bio-inspired Materials: The engineering of new materials using nature as inspiration, or alternatively, using natural frameworks in order to engineer materials with emergent properties that realize enhanced functionality and improved environmental sensing

• Supramolecular Chemistry: The development of new supramolecular motifs that afford enhanced affinity, improved biocompatibility, and/or more precise biomimicry to fully integrate the practice of supramolecular chemistry into new strategies for healthcare

 

Selected Publications:

  1. J.K. Sahoo,*, M.A. VandenBerg,*, M.J. Webber. “Injectable Network Biomaterials via Molecular or Colloidal Self-Assembly Advanced Drug Delivery Reviews 127:185-207; 2018
  2. M.J. Webber, R. Langer. “Drug Delivery by Supramolecular Design” Chemical Society Reviews 46(21):6600-6620; 2017
  3. M.J. Webber “Engineering Responsive Supramolecular Biomaterials: Toward Smart Therapeutics” Bioengineering and Translational Medicine (an AIChE Journal) 1(3):252-266; 2016
  4. M.J. Webber*, E.A. Appel*, B. Vinciguerra, A.B. Cortinas, L.S. Thapa, S. Jhunjhunwala, L. Isaacs, R. Langer, D.G. Anderson. “Supramolecular PEGylation of Biopharmaceuticals” Proceedings of the National Academy of Sciences 113(50):14189-14194; 2016
  5. M.J. Webber*, E.A. Appel*, E.W. Meijer, R. Langer. “Supramolecular Biomaterials.” Nature Materials 15(1):13-26; 2016

News

Two CBE professors named 2020 ACS PMSE Young Investigators

July 29, 2020

Jennifer L. Schaefer and Matthew J. Webber have been named 2020 Polymeric Materials: Science and Engineering Young Investigators by the PMSE Division of the American Chemical Society.

Two CBE professors named 2020 ACS PMSE Young Investigators

July 28, 2020

Jennifer L. Schaefer and Matthew J. Webber have been named 2020 Polymeric Materials: Science and Engineering Young Investigators by the PMSE Division of the American Chemical Society.

Five engineering faculty receive 2020 NSF CAREER awards

June 30, 2020

Five engineering faculty members received National Science Foundation (NSF) Early Career Development (CAREER) awards in 2020, bringing the total CAREER award winners in the College of Engineering to 31 over the last five years.

Webber receives 2020 NSF CAREER Award

May 12, 2020

Matthew J. Webber, assistant professor of chemical and biomolecular engineering, has received a 2020 National Science Foundation Early Career Development (CAREER) Award, the highest honor given by the U.S. government to young faculty members in engineering and science.

Replacing traditional type 1 diabetes management with a glucose-responsive hydrogel

March 1, 2020

Researchers at the University of Notre Dame are working to engineer a safe and effective injectable glucose-responsive hydrogel that could limit the long-term effects of insulin dependence and be administered in a single daily dose.