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Matthew Webber

Matthew J Webber


Phone: 574-631-4246

Office: 205B McCourtney Hall


Ph.D. Biomedical Engineering, Northwestern University, 2011

M.S Biomedical Engineering, Northwestern University 2009

B.S. Chemical Engineering, University of Notre Dame, 2006

Summary of Activities/Interests

Research interests:

• Supramolecular Biomaterials: The use of non-covalent molecular recognition motifs to engineer highly tunable, dynamic, modular, and bioactive materials for biomedical and biological applications (see Webber et al. Nature Materials 2016)

• “Smart” Drug Delivery and Diagnostics: The development of new strategies to deliver drugs, therapeutic proteins, or diagnostic agents that are capable of sensing and responding to spatiotemporal indicators of disease and/or overcoming physiologic barriers imposed by complexities of disease pathology (see Webber & Langer Chem Soc Rev 2017)

• Bio-inspired Materials: The engineering of new materials using nature as inspiration, or alternatively, using natural frameworks in order to engineer materials with emergent properties that realize enhanced functionality and improved environmental sensing

• Supramolecular Chemistry: The development of new supramolecular motifs that afford enhanced affinity, improved biocompatibility, and/or more precise biomimicry to fully integrate the practice of supramolecular chemistry into new strategies for healthcare


Selected Publications:

  1. J.K. Sahoo,*, M.A. VandenBerg,*, M.J. Webber. “Injectable Network Biomaterials via Molecular or Colloidal Self-Assembly Advanced Drug Delivery Reviews 127:185-207; 2018
  2. M.J. Webber, R. Langer. “Drug Delivery by Supramolecular Design” Chemical Society Reviews 46(21):6600-6620; 2017
  3. M.J. Webber “Engineering Responsive Supramolecular Biomaterials: Toward Smart Therapeutics” Bioengineering and Translational Medicine (an AIChE Journal) 1(3):252-266; 2016
  4. M.J. Webber*, E.A. Appel*, B. Vinciguerra, A.B. Cortinas, L.S. Thapa, S. Jhunjhunwala, L. Isaacs, R. Langer, D.G. Anderson. “Supramolecular PEGylation of Biopharmaceuticals” Proceedings of the National Academy of Sciences 113(50):14189-14194; 2016
  5. M.J. Webber*, E.A. Appel*, E.W. Meijer, R. Langer. “Supramolecular Biomaterials.” Nature Materials 15(1):13-26; 2016


Matthew Webber receives American Diabetes Association’s Accelerator Award

February 19, 2019

The American Diabetes Association has announced that it will fund a $1.625 million Accelerator Award to Matthew Webber, assistant professor in the Department of Chemical and Bimolecular Engineering at the University of Notre Dame, to research and develop materials capable of sensing critical drops in blood glucose.

NDnano announces 2018 Seed Grant Program Recipients

July 18, 2018

Nine faculty members from the University of Notre Dame’s College of Engineering and College of Science have been awarded four grants through the Center for Nano Science and Technology (NDnano) Seed Grant Program. 

Webber Named One of 35 Under 35 by AIChE

August 11, 2017

Assistant Professor Matthew Webber,has been named one of the 35 under 35 inaugural class of professionals by the American Institute of Chemical Engineers.

Webber Named to Class of 2017 Emerging Investigators

July 27, 2017

Biomaterials Science has named Matthew Webber, assistant professor of chemical and biomolecular engineering and director of the Supramolecular Engineering Laboratory at the University of Notre Dame, to its 2017 Class of Emerging Investigators.

Harper Cancer Research Institute Names 2017 Summer Undergraduate Research Fellowships

May 4, 2017

Congratulations to Harper Cancer Research Insitute's (HCRI) 2017 Summer Undergraduate Research Fellows! The $4500 fellowship is provided to undergraduate members of HCRI working on a cancer-related project this summer.

New Method Improves Stability, Extends Shelf Life of Protein Drugs

December 5, 2016

A new study appearing in the Proceedings of the National Academy of Sciences and led by Assistant Professor Matthew Webber reveals a new way to improve the stability of common protein drugs and extend shelf life.


Graduate Students: