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Matthew Webber

Matthew J Webber

Email: mwebber@nd.edu

Phone: 574-631-4246

Office: 205B McCourtney Hall

Education

Ph.D. Biomedical Engineering, Northwestern University, 2011

M.S Biomedical Engineering, Northwestern University 2009

B.S. Chemical Engineering, University of Notre Dame, 2006

Summary of Activities/Interests

Research interests:

• Supramolecular Biomaterials: The use of non-covalent molecular recognition motifs to engineer highly tunable, dynamic, modular, and bioactive materials for biomedical and biological applications (see Webber et al. Nature Materials 2016)

• “Smart” Drug Delivery and Diagnostics: The development of new strategies to deliver drugs, therapeutic proteins, or diagnostic agents that are capable of sensing and responding to spatiotemporal indicators of disease and/or overcoming physiologic barriers imposed by complexities of disease pathology (see Webber & Langer Chem Soc Rev 2017)

• Bio-inspired Materials: The engineering of new materials using nature as inspiration, or alternatively, using natural frameworks in order to engineer materials with emergent properties that realize enhanced functionality and improved environmental sensing

• Supramolecular Chemistry: The development of new supramolecular motifs that afford enhanced affinity, improved biocompatibility, and/or more precise biomimicry to fully integrate the practice of supramolecular chemistry into new strategies for healthcare

 

Selected Publications:

  1. J.K. Sahoo,*, M.A. VandenBerg,*, M.J. Webber. “Injectable Network Biomaterials via Molecular or Colloidal Self-Assembly Advanced Drug Delivery Reviews 127:185-207; 2018
  2. M.J. Webber, R. Langer. “Drug Delivery by Supramolecular Design” Chemical Society Reviews 46(21):6600-6620; 2017
  3. M.J. Webber “Engineering Responsive Supramolecular Biomaterials: Toward Smart Therapeutics” Bioengineering and Translational Medicine (an AIChE Journal) 1(3):252-266; 2016
  4. M.J. Webber*, E.A. Appel*, B. Vinciguerra, A.B. Cortinas, L.S. Thapa, S. Jhunjhunwala, L. Isaacs, R. Langer, D.G. Anderson. “Supramolecular PEGylation of Biopharmaceuticals” Proceedings of the National Academy of Sciences 113(50):14189-14194; 2016
  5. M.J. Webber*, E.A. Appel*, E.W. Meijer, R. Langer. “Supramolecular Biomaterials.” Nature Materials 15(1):13-26; 2016

News

Researchers develop drug-targeting molecules to improve cancer treatment

June 12, 2019

Researchers from the University of Notre Dame have developed small drug-targeting molecules that may be hundreds to thousands of times more effective at delivering potent drugs to desired sites of disease, including cancer.

Researchers develop drug-targeting molecules to improve cancer treatment

June 12, 2019

Researchers from the University of Notre Dame have developed small drug-targeting molecules that may be hundreds to thousands of times more effective at delivering potent drugs to desired sites of disease, including cancer.

Researchers develop drug-targeting molecules to improve cancer treatment

June 12, 2019

Researchers from the University of Notre Dame have developed small drug-targeting molecules that may be hundreds to thousands of times more effective at delivering potent drugs to desired sites of disease, including cancer.

Webber receives 2019 3M Non-tenured faculty award

April 22, 2019

Matthew Webber, assistant professor of chemical and biomolecular engineering at the University of Notre Dame, has been named a recipient of the 2019 3M Non-tenured Faculty Award.

Webber receives 2019 3M Non-tenured faculty award

April 22, 2019

Matthew Webber, assistant professor of chemical and biomolecular engineering at the University of Notre Dame, has been named a recipient of the 2019 3M Non-tenured Faculty Award.