Category: Research and Innovation

A smiling engineer in a green blazer and glasses stands in a lab with students in white coats working at equipment.

Notre Dame engineer receives inaugural ARPA-H Emerging Health Innovators award to power lymphatic disease research

As many as 10 million people in the United States live with lymphedema, a chronic condition causing severe, painful swelling of the limbs. Secondary lymphedema occurs when a person’s lymph nodes are damaged, blocked, or impaired. Globally, the most prevalent trigger of secondary lymphedema is …

Miniature Underwater Vehicle (MUR) in field test, Lake Crampton, UNDERC, Wisconsin

Lost at sea no more: New AI platform helps underwater robots get their bearings 

Shifting sunlight, bubbles, and silt constantly interfere with an autonomous underwater vehicle’s (AUVs) ability to find its way. GPS can’t help them, since water blocks its signals. Sound waves—the pings made famous by submarines—travel rapidly through water, yet they too have their …

Yanliang Zhang

Notre Dame Engineering and Harvard Medical School collaborate on 4-year NIH project to create lab-grown organs

While scientists have successfully printed small patches of human tissue, scaling those tissues into full-sized organs has remained elusive. In natural organisms, every cell must be within roughly 100 to 200 micrometers—about the thickness of two human hairs—of a blood vessel to receive oxygen …

Jonathan Chisum

Professor Jonathan Chisum awarded FCC experimental license to advance 5G research at Notre Dame

The Wireless Institute is pleased to announce that Dr. Jonathan Chisum has been granted a two-year experimental license by the Federal Communications Commission (FCC), enabling advanced wireless research and real-world 5G experimentation on the University of Notre Dame campus. This experimental …

Several glass vials containing bright blue fluorescent liquid on a dark surface under blue light.

Notre Dame researchers to advance detection and community knowledge of opioids, including new variants

Four teams of researchers across the College of Science and the College of Engineering have been selected to receive seed funding from the Notre Dame Sensor Initiative (NDSI) for research advancing affordable, fast, and accurate platforms for on-site opioid detection. As opioid …

A pipette places drops of green liquid onto a microscope slide containing a small device

Heart-on-a-chip device identifies youth-enhancing “cocktail” to repair old hearts

The heart is a pump that wears out over time—that, at least, was the prevailing view. New research has shown that the heart’s aging results from changes in intercellular communications, which tell heart cells, sometimes even healthy ones, to stiffen and break down. By decoding these complex …

Katharine White and Donny Hanjaya-Putra

Notre Dame researchers uncover the molecular driving force behind hallmark of aggressive, metastatic cancers

To invade healthy tissues and continue growing, aggressive cancers mimic and circumvent the body’s native piping system of veins and arteries. Through this process, known as vasculogenic mimicry (VM), tumor cells form fluid-conducting channels that transport blood, oxygen, and nutrients directly …

A young woman looks at a microscope slide that has a dab of clear gel in the middle of it

3D-bioprinted model offers new way to study and treat obesity-related heart disease

Heart disease is the leading cause of death among people with obesity, a condition affecting one in eight people worldwide. Studies show that fat around the heart can fuel inflammation, damage heart muscle cells, disrupt heart rhythm and increase the risk of heart failure, but the precise …

Glowing orange light waves travel along and bend around a geometric, triangular-patterned surface, illustrating researchers guiding light through a structured material to form a 6G terahertz “super-antenna.”

Using geometry, researchers coax light into 6G terahertz “super-antenna”

Engineers have long focused their efforts on confining signal-carrying photons to chips. Every photon that escapes, they reasoned, is information lost. But one group of researchers has stood that paradigm on its head. By deliberately “leaking” photons into the air, they created, not the …

Two researchers in white lab coats and safety glasses work in a lab. A man in blue gloves uses a tool to transfer liquid into a small container near a multi-well plate with reddish liquid. A woman observes him, smiling softly.

Physical pressure on the brain triggers neurons’ self-destruction programming

To think, feel, talk and move, neurons send messages through electrical signals in the brain and spinal cord. This intricate communication network is built of billions of neurons connected by synapses and managed and modified by glial cells. When neurons die, this communication network is …